The jinchuriki (Literally meaning "Power of Human Sacrifice") are humans that have Tailed Beasts sealed within them. They exhibit extraordinary powers due to the immense chakra reserves they possess.
The jinchuriki are typically lonely and miserable people, as they are often shunned and discriminated by their fellow villagers, who view them as the tailed beasts themselves. According to Deidara, the first two jinchuriki Akatsuki had captured loathed humanity, and their villages were in fact glad to be rid of them. However, some jinchuriki refuse to waver, even though they have been shunned, and they eventually earned respect. Such examples include Naruto Uzumaki, Killer Bee, Yagura, Yugito Nii, and Gaara.